Vitamin C and collagen

Why stability is crucial

Pure ascorbic acid is more bioavailable, but less stable than its derivatives. Without protection it can oxidise the amino acids of the collagen and reduce the overall effectiveness. Encapsulation, stable derivatives, a controlled pH value, packaging under inert gas or the use of antioxidants significantly improve shelf life and synergy with collagen. Stable forms are therefore essential for the longevity of a product.

Factors that influence stability

• Light & heat: UV light and heat accelerate degradation and lead to discolouration and loss of effectiveness.
• pH value: A high (alkaline) pH value makes ascorbic acid more susceptible to photochemical decomposition.
• Proximity to other ingredients: Substances such as niacinamide can increase the instability under UV light; stable derivatives such as magnesium ascorbyl phosphate offer more protection.
• Antioxidants: Additional antioxidants contribute to the protection of the vitamin C.
• Formulation: Balanced ingredients and a controlled pH value prevent undesirable reactions such as the Maillard reaction (browning) between proteins and ascorbic acid.

Stability and preservation — according to the manufacturer

According to the manufacturer, an accelerated six-month stability test to ICH standards was carried out on the liquid formulas: storage at 40 °C and 75 % relative humidity in the manufacturer's GMP-certified laboratory, with pH value, viscosity, density, microbial load and vitamin C content analysed every 30 days. Bettervita does not run laboratory tests itself; the test reports are held by the manufacturer.

Also according to the manufacturer, a preservative efficacy (challenge) test in accordance with the European Pharmacopoeia was carried out.

A powerful duo

Vitamin C is involved in the body's collagen formation: it contributes to normal collagen formation — an authorised health claim. Can you take both together? Yes. For hydrolysed collagen peptides themselves there are controlled studies on skin elasticity and wrinkle volume (Proksch et al., 2014) and on joint discomfort (Clark et al., 2008).

What you should avoid

• Coffee & tea: Drinks with a high tannin content can bind proteins — wait around 30 minutes after taking it.
• Protein-/fibre-rich meals: processed together, collagen absorption can decrease.
• Smoking, too much sugar and alcohol: inhibit collagen production and accelerate breakdown (glycation).
• Too much sun: UV radiation breaks down collagen — daily sun protection is a must.
• Lack of sleep: Sleep is crucial for collagen repair and production.

Who should be careful

• Kidney diseases or kidney stones: Collagen is a protein; with a high intake, seek medical advice and drink enough water.
• Allergies: if you have a fish/shellfish allergy, avoid marine collagen and check the origin.
• Autoimmune diseases or medication: if you take blood thinners, NSAIDs or blood pressure medication, consult your doctor beforehand.